A multi-stage process utilizing one or more radiation sensors on a distributed network for the detection and identification of radiation, explosives, and special materials within a shipping container. The sensors are configured as nodes on the network. The system collects radiation data from one or more nodes and compares the collected data to one or more stored spectral images representing one or more isotopes to identify one or more isotopes present. The identified one or more isotopes present are corresponded to possible materials or goods that they represent. The possible materials or goods are compared with the manifest relating to the container to confirm the identity of materials or goods contained in the container or to detect and/or identify unauthorized materials or goods in the container. For shielded materials, explosives and other types of material detection, a neutron pulse device could be incorporated into the system.