A combination sealing system and seal activation system for use with a combination of a panel and a frame includes a plurality of sealing systems and a seal activation systems. Each of the sealing systems include an anchor, at least one movable member, and an actuator. The anchor engages one of the panel and the frame, and the anchor movable from a first position to a second position towards the panel. The at least one movable member is positioned in an other of the panel and the frame and moves the anchor between the first position and the second position. The actuator is connected to the at least one movable member and drives the at least one movable member. The seal activation system is connected to each of the actuators of the plurality of sealing systems.