The cervical plate locking mechanism of the present invention is elegant in its design and effective in its performance, and utilizes a plate with holes that each incorporate a locking lip structure and locking screws that each incorporate a head portion having petal structures that are outwardly biased prior to insertion via an internally-disposed c-ring or the like. Advantageously, the lead-in torque of each of the locking screws is less than the lead-out torque of each of the locking screws. Thus, reverse threading or backing out is prevented. Alternatively, the cervical plate locking mechanism of the present invention utilizes a locking plate having petal structures that are inwardly biased prior to insertion of the head portion of the locking screws via an externally-disposed c-ring or the like.